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Klinische Studien: Unterer GI-Trakt

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Klinische Studien zu onkologischen Erkrankungen im Bereich Unterer GI-Trakt am CCCC Berlin – unter anderem Adenokarzinom.

AIO-KRK-0324 (QUINTIS)

Phase II · Status: active · Adenokarzinom

A Randomized Phase II Trial Evaluating Fruquintinib in Combination With Tislelizumab in Microsatellite Stable / Proficient Mismatch Repair (MSS/pMMR) Metastatic Colorectal Cancer Without Active Liver Metastases DE ↗

AIO-KRK-0418 (FIRE-9/PORT)

Phase III · Status: active · Adenokarzinom

Post-resection/Ablation Chemotherapy in Patients With Metastatic Colorectal Cancer Prospective, Randomized, Open, Multicenter Phase III Trial to Investigate the Efficacy of Active Post-resection/Ablation Therapy in… DE ↗

AIO-KRK-0620 (FIRE-10/ PROTECTOR)

Phase III · Status: active · Adenokarzinom

Pre-Operative Treatment in rEseCTable cOlon cancer (PROTECTOR) - Prospective, randomized, open, multicenter Phase III trial to investigate the efficacy preoperative system therapy in advanced colon cancer DE ↗

ARO 2024-13

Phase III · Status: active · Adenokarzinom

Radiochemotherapy With Concomitant Deep Regional Hyperthermia in Locally Advanced Rectal Cancer. A Prospective, Randomized Phase III Trial. DE ↗

C6461003 Pfizer

Phase III · Status: active · Adenokarzinom

AN INTERVENTIONAL, PHASE 3, DOUBLE-BLIND, RANDOMIZED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF PF-08634404 IN COMBINATION WITH CHEMOTHERAPY VERSUS BEVACIZUMAB IN COMBINATION WITH CHEMOTHERAPY IN TREATMENT-NAIVE… DE ↗

FIRE 8

Phase II · Status: active · Adenokarzinom

Prospective, Randomized, Open, Multicenter Phase II Trial to Investigate the Efficacy of Trifluridine/Tipiracil Plus Panitumumab Versus Trifluridine/Tipiracil Plus Bevacizumab as First-line Treatment of Metastatic… DE ↗

Hemoscreen

Nicht zutreffend · Status: active · Adenokarzinom

Hemoscreen DE ↗

ISO-CC-010

Phase I/II · Status: active · Adenokarzinom

A Phase 1b/2 Study of Arfolitixorin Combined With 5-fluorouracil, Oxaliplatin, and Bevacizumab in First-line Treatment of Metastatic Colorectal Cancer DE ↗

MEN1611-02

Phase I/II · Status: active · Adenokarzinom

OPEN-LABEL, MULTICENTRE, PHASE IB/II STUDY OF MEN1611, A PI3K INHIBITOR, AND CETUXIMAB IN PATIENTS WITH PIK3CA MUTATED METASTATIC COLORECTAL CANCER FAILING IRINOTECAN, OXALIPLATIN, 5-FU AND ANTI-EGFR CONTAINING REGIMENS DE ↗

MR Rektumkarzinom

Nicht zutreffend · Status: active · Adenokarzinom

Lokoregionäres Staging des Rektumkarzinoms mittels quantitativer multiparametrischer Magnetresonanztomografie DE ↗

OrigAMI-2

Phase III · Status: active · Adenokarzinom

A Randomized, Open-label Phase 3 Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or… DE ↗

OrigAMI-3

Phase III · Status: active · Adenokarzinom

A Randomized, Open-label Phase 3 Study of Amivantamab + FOLFIRI Versus Cetuximab/Bevacizumab + FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Recurrent, Unresectable or Metastatic Colorectal Cancer Who Have… DE ↗

RESEX

Nicht zutreffend · Status: active · Adenokarzinom

RESEX - Auswirkungen der multimodalen Rektum-Chirurgie auf die Anorektal-, Urogenital- und Sexualfunktion DE ↗

SAGITTARIUS

Phase II · Status: active · Adenokarzinom

Intensity of chemotherapy after surgery determined by DNA detection in blood of patients with local colon cancer DE ↗

SGNTUC-029 (MOUNTAINEER-03)

Phase III · Status: active · Adenokarzinom

An Open-label Randomized Phase 3 Study of Tucatinib in Combination with Trastuzumab and mFOLFOX6 versus mFOLFOX6 given with or without either Cetuximab or Bevacizumab as First-line Treatment for Subjects with HER2+… DE ↗

WO42758 (INTRINSIC)

Phase I · Status: active · Adenokarzinom

A Phase I/Ib Global, Multicenter, Open-label Umbrella Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC) DE ↗

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